Dimensions of Affect, Mood, And Neural Circuitry 
Underlying Distress
Diamond                 Study

The Diamond Study takes place over a span of several visits; the number of visits is dependent upon whether participants are eligible to participate. The study begins with a brief telephone screen to determine eligibility. If eligible, participants will then come in for a clinical evaluation/screening visit involving multiple  self-report questionnaires. That visit takes approximately 3-4 hours. Subjects will be paid for their participation for each visit.


If the subject is still eligible for the study at that point, they will be scheduled for an fMRI scan.


Scans take place at the University of Pittsburgh Medical Center inside Presbyterian Hospital at the Magnetic Resonance Research Center (MRRC), which is located at this link.

What to Expect

What is fMRI?

Functional magnetic  resonance imaging (fMRI) is used to measure changes in blood flow to certain areas of the brain as people perform certain cognitive and emotion tasks. In this study, we use fMRI to help us understand how the brain works in people experiencing distress.  


Subjects will lie on a table that moves part way into a large tube containing a magnetic field.  A cylinder-like coil is placed around the subject’s head as the images are taken and the participant is asked to keep still during this time.  


The imaging cannot be felt and the procedure is non-invasive. There is only one fMRI session during the study. The remainder of sessions are follow-up visits involving the completion of questionnaires.